Diagnostic Delay in Patients with Eosinophilic Gastritis and/or Duodenitis: A Population-Based Study
نویسندگان
چکیده
BackgroundEosinophilic gastritis and/or eosinophilic duodenitis (EG/EoD) is characterized by persistent symptoms and elevated eosinophils in the gastrointestinal tract. Limited disease awareness lack of diagnostic guidelines suggest that patients may remain undiagnosed or endure delay.ObjectiveTo characterize path to diagnosis for with EG/EoD a representative population.MethodsIn this observational cohort study, 4108 eligible diagnosed between 2008 2018 were identified an administrative claims database United States. Patient medical claim history was analyzed describe events related diagnosis.ResultsMean year from symptom presentation 3.6; factors contributing delay included delayed gastroenterologist referral, esophagogastroduodenoscopy (EGD), biopsy collection histopathologic evaluation. Missed on index EGD occurred 38.2% patients, resulting mean increase 1.6 years time versus EGD. Patients presented nonspecific 44.3% another condition before diagnosis. Independent predictors >2-year adult age; prior irritable bowel syndrome, functional dyspepsia, gastric/peptic ulcer; use other procedures such as colonoscopy; presence edema; certain allergic diseases.ConclusionsThis study found experienced average 3.6 initial revealed several delay. We hope these findings, together heightened standardization guidelines, will improve journey EG/EoD. Eosinophilic To population. In Mean diseases. This
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ژورنال
عنوان ژورنال: The Journal of Allergy and Clinical Immunology: In Practice
سال: 2021
ISSN: ['2213-2201', '2213-2198']
DOI: https://doi.org/10.1016/j.jaip.2020.12.054